Raloxifene: translate of russian instruction

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Indications of Raloxifene
Osteoporosis (preventive maintenance at women in the postclimacteric period and after hyperectomy).

Contra-indications of Raloxifene
Hypersensitivity, genital age, pregnancy, the lactation period; trombs (including in the anamnesis), a thrombosis of deep veins, the retina vein thrombosis, the expressed infringements of function of a liver, long immobilisation.

Collateral actions of Raloxifene
(blood “inflow” to a face skin), spasms leg muscles, trombemboly, a thrombosis of deep veins, a retina vein thrombosis; peripheral hypostases.

Way of application and dose of Raloxifene
Inside, 60 mg/sut (irrespective of food intake), are long.

Special instructions of Raloxifene
It is not recommended to apply in a combination to an estrogen. At occurrence of diseases or the conditions conducting to long immobilisation, preparation reception is necessary for cancelling and renewing under condition of return of full mobility. Against treatment raloxifene it is recommended to appoint in addition preparations Ca2 +.

Interaction of Raloxifene
At simultaneous appointment of indirect anticoagulants small reduction protrombine time is marked. Colestiramin essentially reduces всасывание and intestinally-hepatic transport. Ampicillin reduces Cmax, without influencing the general degree and speed of deducing.

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